
Trial Talk
UCL Minds
The Trial Talk Podcast explores how our work at the MRC Clinical Trials Unit at UCL is improving health in the UK and worldwide. In this new series, we will hear from world-leading experts about the studies we carry out. We will get inside trials on cancer, infections, and neurodegenerative diseases, explore how public and patient involvement is shaping our studies, and discover new ways to run smarter studies.
Categorieën: Onderwijs
Luister naar de laatste aflevering:
At the start of October, lots of the Unit’s clinical trials methodology researchers travelled to Edinburgh, for the 7th International Clinical Trials Methodology Conference (ICTMC). ICTMC is the largest academic-led conference on clinical trials, bringing together trialists from across the globe to present their latest work in trials methodology. This year's conference featured a wide variety of workshops, talks and poster presentations from MRC Clinical Trials Unit researchers. I
n this latest episode of the Trial Talk podcast, four of the Unit’s early career researchers discuss the work they presented at ICTMC 2024. Gideon Darko Asamoah tells us how he will deliver a core outcome set for trials in severe malaria; Jingyi Xuan describes her project addressing intercurrent events in platform trials; Dongquan Bi discusses the effects of different cluster sizes in cluster trials; and finally, Kate Roberts explains how she aims to improve the wording around consent for accessing trial participants' healthcare records.
For questions or feedback on the series, message us at mrcctu.engage@ucl.ac.uk
For more information and to access the transcript: bit.ly/4f9grVi
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More resources:
• Developing a core outcome set for severe malaria trials poster: www.mrcctu.ucl.ac.uk/posters/identi…nd-caregivers/
• Specifying estimands and estimators in trials with complex designs poster: www.mrcctu.ucl.ac.uk/posters/specif…mplex-designs/
• Demystifying estimands in cluster-randomised trials paper in Statistical Methods in Medical Research: journals.sagepub.com/doi/10.1177/09622802241254197
• Estimands in cluster-randomised trials paper in International Journal of Epidemiology: academic.oup.com/ije/article/52/1/107/6644521
• Current practice around the use of estimands in cluster randomised trials, and the impact of informative cluster size on inference poster: www.mrcctu.ucl.ac.uk/posters/curren…on-inferences/
• ICTMC 2024 Poster 167 – A rap song (Lyrics by Dongquan Bi, beat by David Fitzgerald): youtu.be/s7qZ5TnOlWU?si=iXwfFfSAWwJ-fAmk
• CrossWord poster: www.mrcctu.ucl.ac.uk/posters/crossw…ing-materials/
Date of episode recording: 2024-10-30T00:00:00Z
Duration: 00:25:09
Language of episode: English
Presenter:Charlotte Hartley
Guests: Gideon Darko Asamoah, Jingyi Xuan, Donguan Bi, Kate Roberts
Producer: Charlotte Hartley
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26 - Episode 8: International Clinical Trials Methodology Conference 2024 roundup - Early Careers Edition Thu, 31 Oct 2024
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25 - Episode 7: Preventing multidrug-resistant tuberculosis Wed, 25 Sep 2024
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24 - Episode 6: The OPTIC study: Patient views on optimising immunotherapy in cancer Mon, 01 Jul 2024
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23 - Episode 5: Patient and Public Involvement (PPI) in clinical trials Tue, 04 Jun 2024
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22 - Episode 4: Estimands - Answering the right research questions Fri, 26 Apr 2024
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21 - Episode 3: Subgroup analysis - Who benefits most from a treatment? Thu, 14 Mar 2024
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20 - Episode 2: Lessons from UKCTOCS, a large-scale trial in ovarian cancer screening Mon, 12 Feb 2024
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19 - Episode 1: Careers in TB trials with Andrew Nunn and Sarah Meredith Thu, 01 Feb 2024
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18 - Episode 10 (part 2): World AIDS Day: Bringing hope through research to young people living with HIV with Lungile Jafta and Gugu Mon, 04 Dec 2023
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17 - Episode 10 (part 1): World AIDS Day: Closing the gap between adults and children with Anna Turkova and Philippa Musoke Mon, 04 Dec 2023
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16 - Episode 9 (part 4): Octopus: Involvement of people affected by MS with Susan Scott Fri, 10 Nov 2023
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15 - Episode 9 (part 3): Octopus: The patients’ experience with Dawn Lyle and Matthew Justin Thu, 02 Nov 2023
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14 - Episode 9 (part 2): Octopus: Introducing the trial with Jeremy Chataway Thu, 26 Oct 2023
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13 - Episode 9 (part 1): Octopus: The multiple sclerosis landscape with Jeremy Chataway, Dawn Lyle and Matthew Justin Thu, 19 Oct 2023
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12 - Episode 8: Optimising treatments with the new MAMS-ROCI design Wed, 20 Sep 2023
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11 - Episode 7: STAMPEDE (part 3): Impact and legacy Tue, 12 Sep 2023
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10 - Episode 7: STAMPEDE (part 2): The role of the patient voice Tue, 12 Sep 2023
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9 - Episode 7: STAMPEDE (part 1): A new era for prostate cancer research Wed, 16 Aug 2023
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8 - Episode 6: The REFINE trial: how can we improve the way we give cancer immunotherapy? Tue, 18 Jul 2023
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7 - Episode 5: How can clinical trials make the most of healthcare systems data? Tue, 27 Jun 2023
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6 - Episode 4: Neonatal infections (part 2): How the NeoSep1 trial will help treat sick newborns Mon, 12 Jun 2023
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5 - Episode 4: Neonatal infections (part 1): The NeoOBS study and the global challenge of neonatal sepsis Mon, 22 May 2023
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4 - Episode 3: The STREAM2 trial - how should we treat multi-drug resistant tuberculosis? Fri, 24 Mar 2023
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3 - Episode 2: Part 2 - Sharing the Results of Clinical Trials with Participants Thu, 24 Nov 2022
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2 - Episode 2: Part 1 - Sharing Results of Clinical Trials with Participants Thu, 24 Nov 2022
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1 - Episode 1: The ARCHERY study – Can AI transform the way we plan radiotherapy treatment globally? Thu, 24 Nov 2022